妮可尔（莎朗·斯通 Sharon Stone 饰）和米娅（伊莎贝尔·阿佳妮 Isabelle Adjani 饰）可能是这个世界上关系最密切的两个女人了，然而，她们不是朋友却是敌人，因为两人共同侍奉着同一个男人，那就是米娅的丈夫盖伊（查兹·帕尔明特瑞 Chazz Palminteri 饰）。
　　盖伊是个狂妄又凶残的混蛋，他不仅不为自己的三心二意感到羞愧，更是软硬兼施，将两个女人牢牢的拴在自己的身边。长久的压抑和郁闷之中，妮可尔和米娅决定联手除掉这个可恶的男人，可是，当她们将一个绝妙的计划付诸行动之后，两人的身边开始发生一些无法用常理来解释的神秘事件。与此同时，女侦探雪莉（凯西·贝茨 Kathy Bates 饰）的步步紧逼让妮可尔和米娅明白，她们目前的处境并不乐观。

　　In the fourth season of this award-winning show, the action at New York City's 15th Precinct is as hectic as ever. While Lieutenant Fancy continues as precinct commander, Detective Andy Sipowicz, although still a bit rough around the edges, has mellowed with the birth of his son. Detective Bobby Simone and Detective Diane Russell take the next step in their relationship, James Martinez becomes the Squad Delegate, and Greg Meadavoy considers becoming a surrogate father. But one thing that hasn't changed is the squad's determination to make sure the bad guys get their day in court and to also attempt to maintain a touch of normalcy in their personal lives even as they investigate cases that often put them directly in the line of fire.