克里斯·钱尼出狱后，为了履行一个旧日的承诺而踏上了一场危险的旅程。然而，当他绑架了黑帮大佬的女儿伊丽莎时，他发现自己陷入了危险之中。伊丽莎的父亲文森特向整个犯罪地下世界发出了悬赏令，要求活捉她回来。而精神病患者杀手埃尔科沃加入追捕行列并非为了金钱，而是为了对文森特家族进行个人报复。克里斯必须躲避伊丽莎强大的父亲和一心复仇的冷酷杀手，以足够长的时间来告诉伊丽莎那个一直隐藏在她身边。

　　讲述匹兹堡一家医院的医护人员的日常生活。

　　Charlie Cale is back on the run, and in Season 2 we’ve taken her journey to the next level one murder mystery at a time," Johnson and Lyonne teased in a joint statement. "From minor league baseball to big box retail, from funeral homes to alligator farms and even a grade school talent show, Charlie navigates her crime solving existential road-trip with deadpan wit, human empathy, and her signature uncanny lie-detecting ability.